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MS has affected a family member, so I have tons of information. Here is a sample:
YOU CAN MOVE, AND YOUR BODY CAN RESPOND
exercise therapy can be beneficial for patients with MS Cochrane Database Syst Rev. 2005 Jan 25
skeletal muscle is unaffected by MS. Arch Phys Med Rehabil. 2005 Feb;86(2):224-9
Hyperthermia can be caused through sun exposure, exercise, and infection.
Sweat gland function in individuals with MS is impaired J Appl Physiol. 2005 Jan 7
Subjects with MS participating in either a 6-month yoga class or exercise class showed significant improvement Neurology.
2004 Jun 8;62(11):2058-64
MS patients are capable of making positive adaptations to resistance training that are associated with improved ambulation
and decreased fatigue Mult Scler. 2004 Dec;10(6):668-74.
regular TCC (Tai Chi Chuan) exercise may have an association with higher BMD and better neuromuscular function J Bone
Miner Metab. 2005;23(2):186-90.
IMT (Inspiratory muscle training) had a beneficial effect on inspiratory muscle strength in patients with MS Arch Phys
Med Rehabil. 2003 Jul;84(7):994-9
ARE YOU GETTING ENOUGH VITAMIN D?
new biological functions of 1,25(OH)2D in regulating cell growth, modulating the immune system and modulating the renin-angiotensin
system provides an explanation for why diminished sun exposure at higher latitudes is associated with increased risk of dying
of many common cancers, developing type 1 diabetes and multiple sclerosis, and having a higher incidence of hypertension
Recent Results Cancer Res. 2003;164:3-28
Administration of the active metabolite 1,25-(OH)(2)D in mice and rats with experimental allergic encephalomyelitis (EAE,
an animal model of MS) not only prevented, but also reduced disease activity. Eur J Clin Nutr. 2004 Aug;58(8):1095-109
One mcg per day of Vitamin D(3) (cholecalciferol) increases circulating 25(OH)D by about 1 nmol/L (0.4 ng/mL). If 70 nmol/L
is regarded as a minimum desirable target 25(OH)D concentration, then current recommendations of 15 mcg per day do not meet
the criterion of an RDA. Randomized clinical trials using 20 mcg (800 IU) per day of Vitamin D show that this suppresses parathyroid
hormone, preserves bone mineral density, prevents fractures, lowers blood pressure and improves balance J Steroid Biochem
Mol Biol. 2004 May;89-90(1-5):575-9.
Total-body sun exposure easily provides the equivalent of 250 microg (10000 IU) vitamin D/d, suggesting that this is a
physiologic limit. Except in those with conditions causing hypersensitivity, there is no evidence of adverse effects with
serum 25(OH)D concentrations <140 nmol/L, which require a total vitamin D supply of 250 microg (10000 IU)/d to attain.
Published cases of vitamin D toxicity with hypercalcemia, for which the 25(OH)D concentration and vitamin D dose are known,
all involve intake of > or = 1000 microg (40000 IU)/d. Am J Clin Nutr. 1999 May;69(5):842-56
CAN WE AT LEAST TALK ABOUT SWANK?
Lancet. 1990 Jul 7;336(8706):37-9. Related Articles, Links
Effect of low saturated fat diet in early and late cases of multiple sclerosis.
Swank RL, Dugan BB.
Department of Neurology, Oregon Health Sciences University, Portland 97201.
144 multiple sclerosis patients took a low-fat diet for 34 years. For each of three categories of neurological disability
(minimum, moderate, severe) patients who adhered to the prescribed diet (less than or equal to 20 g fat/day) showed significantly
less deterioration and much lower death rates than did those who consumed more fat than prescribed (greater than 20 g fat/day).
The greatest benefit was seen in those with minimum disability at the start of the trial; in this group, when those who died
from non-MS diseases were excluded from the analysis, 95% survived and remained physically active.
PMID: 1973220 [PubMed - indexed for MEDLINE]
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